Subject: Isis Climbs on Patent Promise
Date: Published: 11/11/92 (23 lines)
Source: Wall Street Journal. Copyright Dow Jones & Co. Inc.

    OTC Focus:
    Nasdaq Composite Index Climbs 0.92%
    To 627.76, Rising Fifth Day in a Row
    ----
    By Sara Calian
    Staff Reporter of The Wall Street Journal

    NEW YORK -- The over-the-counter market continued to climb for
 the fifth day in a row, with technology and biotechnology stocks
 leading the upswing.
    Isis Pharmaceuticals increased 1 5/8 to 11 3/4.  The Carlsbad,
 Calif., company said it will be issued a U. S. patent on antisense
 oligonulceotide inhibitors of the human immunodeficiency virus, the
 virus that causes AIDS.  

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