Subject: Biosyn Date: Published: 1/31/92 (43 lines) Source: Wall Street Journal. Copyright Dow Jones & Co. Inc. A Final Visit With Three Start-Up Companies Finds Them Still Hopeful ---- By Brent Bowers Staff Reporter of The Wall Street Journal [16 lines irrelevant to AIDS removed. -- sysop] The president of Biosyn Inc., a Philadelphia developer of products to prevent the spread of AIDS, says several long-delayed marketing and licensing agreements are about to be signed and exults that the Food and Drug Administration is showing unexpected receptiveness to its proposals for clinical testing. Six months pregnant, she says she aims to "go into labor in the office." The New Jersey marketing manager who started Bottle Toppers in her home to make designer outfits for wine bottles says her two new partners have breathed life into the enterprise -- but sales are still disappointing. Even if her business fails, she says, she'll come out ahead because of the knowledge gained. [31 lines irrelevant to AIDS removed. -- sysop] Meantime, Biosyn is switching directions, putting on hold a disinfectant that it once touted because of regulatory demands by the Environmental Protection Agency. By contrast, it says it is making unforeseen progress in developing its virus-killing spermicide, its treatment for oral yeast infections in AIDS patients and its barrier cream for latex gloves. Dr. Malamud says Biosyn's relationship with the FDA is proceeding "much more smoothly than we anticipated," and he says FDA approval for human studies on one or more products is certain this year. [This article is made available here by Dow Jones Co. for the personal and non-commercial use of callers to this bbs, in the hope that it will be of some help to those who are suffering from the disease and others who are seeking to help them.]