Subject: DaunoXome May Be Able To Treat Kaposi's Sarcoma Date: Published: 12/11/91 (34 lines) Source: Wall Street Journal. Copyright Dow Jones & Co. Inc. Business Brief -- Vestar Inc.: DaunoXome May Be Able To Treat Kaposi's Sarcoma Vestar Inc. said clinical results reported at a medical meeting indicate that its drug DaunoXome may have "significant capability" as a treatment for AIDS-related Kaposi's sarcoma. DaunoXome is a formulation of daunorubicin, an established cancer drug that previously wasn't used in AIDs patients. Vestar, based in San Dimas, Calif., reported to the American Society of Hematology annual meeting that 60% of 16 AIDS patients with Kaposi's sarcoma showed a reduction in the number, growth or size of lesions. And 40% showed a stabilization of the cancer, Vestar said. DaunoXome can be used safely with AIDS patients who are also taking AZT, currently the principal treatment for AIDS patients, it reported. Kaposi's sarcoma is characterized by lesions of the skin, mucous membranes, lymph nodes and internal organs. It affects an estimated 15% or more of AIDS patients. Vestar develops, tests, manufactures and markets pharmaceuticals to treat patients with cancer and serious infections, including AIDS. The company said it is doing clinical testing of DaunoXome in Germany, France, the United Kingdom, San Francisco and Los Angeles. [This article is made available here by Dow Jones Co. for the personal and non-commercial use of callers to this bbs, in the hope that it will be of some help to those who are suffering from the disease and others who are seeking to help them.]