Subject: As Many as 380,000 in U. S. Are Expected To Have AIDS by 1992 Date: Published: 6/14/88 89 lines Source: WALL STREET JOURNAL. Copyright Dow Jones & Co. Inc. As Many as 380,000 in U. S. Are Expected To Have AIDS by 1992, Researcher Says --- By Marilyn Chase Staff Reporter of The Wall Street Journal STOCKHOLM -- One new case of acquired immune deficiency syndrome is now being diagnosed in the U. S. every 14 minutes. That's the grim growth rate of the AIDS epidemic, which currently has inflicted 65,000 people in the U. S. and is expected to inflict between 365,000 and 380,000 by 1992, said James Curran, AIDS program director for the U. S. Centers for Disease Control in Atlanta. Europe currently counts 12,200 victims and Africa -- in what officials acknowledge is an underestimate -- reports 11,500. Dr. Curran addressed the "predictions versus the reality" of his agency's AIDS outlook at the fourth international conference on AIDS here Monday. CDC's count of AIDS cases, often criticized and recently blurred by re-definitions of the disease, was defended by the official "as 98.5% accurate" through last year. He said the range in the 1992 forecast stems from two different mathematical models used by researchers at the CDC and Johns Hopkins University in Baltimore. However, when it comes to estimates of the infected population -- that is those who carry the virus but aren't yet sick -- Dr. Curran admitted that CDC's crystal ball has been cloudy. His 1986 estimate of one million infected people was then "almost certainly too high," and he said the current range is only now one million to 1.5 million. To try and get a better grasp on the real numbers of infected people, the CDC now is drawing anonymous blood samples to test for AIDS antibody at 30 hospitals in the nation's midsection. So far, he said, 15 samples from four of the hospitals in the continuing study indicate that about three people per 1,000 carry the AIDS virus -- more than four times the rate of infection in the U. S. military. The rate found by the study, which is designed to be definitive and to squelch second guessing, already is being attacked as too low. Robert Redfield of Walter Reed Army Hospital in Washington, D. C. said in an interview that CDC is sampling only hospitals in the Midwest, and has excluded from its count anyone admitted to the hospitals with cancer, tuberculosis, or any immune weakness suspected of being AIDS related. "It's not the way I would have done it," Dr. Redfield said. "To me, the purpose shouldn't be to minimize the problem, but to find out" how big the problem is. Dr. Redfield, a major in the U. S. Army, has advocated wider blood testing because "people with the AIDS virus have a right to early diagnosis so doctors can treat them early. They're being denied that right." But such statistics gathering carries a political charge to AIDS-patient advocates who fear wider testing may lead to discrimination. John James, who writes a newsletter for the AIDS-drug underground in San Francisco, said "the fear is that American business will follow the military in excluding the infected from sensitive jobs or any job on the presumption that they have AIDS dementia." In Europe, even more than in the U. S., intravenous drug users are accounting for more and more AIDS cases. There, they now make up almost a third of the cases, mainly concentrated in France, Spain and Italy, said Jean-Baptiste Brunet of France. He said AIDS-infected Europeans now number somewhere between 300,000 and 800,000. New cases of AIDS in Europe are doubling every 11 months, and are forecast to top 56,000 by the end of 1989. In Africa, the main risk of AIDS continues to come from heterosexual relations, said Bosenge N'galy of Zaire. Dr. N'galy said the continent's reported 11,500 cases "is clearly an underestimate." The rate of infection across Africa varies from 1% in the Cameroon to 15% in Uganda. Some 18% of blood donors in Rwanda and Zambia are infected, he said. Blood screening for antibodies is still very limited in Africa because of the prohibitively high cost of the antibody test. The infection of as many as 12% of pregnant African women in some areas (half of whose children will be born infected) threatens to undo recent progress against infant mortality in Africa, he said. [This article is made available here by Dow Jones Co. for the personal and non-commercial use of callers to this bbs, in the hope that it will be of some help to those who are suffering from the disease and others who are seeking to help them.]