Subject: Imreg Expects to Post Loss of Up to $300,000 Date: Published: 10/1/85 54 lines Source: Wall Street Journal. Copyright Dow Jones & Co. Inc. Imreg Expects to Post Loss of Up to $300,000 For the Third Quarter NEW ORLEANS -- Imreg Inc., a biotechnology concern, expects to post a third-quarter loss of $250,000 to $300,000, compared with a year-earlier loss of $176,833, Dr. A. Arthur Gottlieb, president and chief executive officer, said. For all of 1985, Imreg expects to post a loss of about $1 million, which is wider than the 1984 loss of $731,989. Imreg, which went public in January 1984, is developing a drug to bolster human immune systems, particularly in victims of acquired immune deficiency syndrome, known as AIDS. Dr. Gottlieb attributed the projected loss to the high cost of clinical testing for Imreg-1, a drug made from the white blood cells of healthy individuals. To develop such a drug, Dr. Gottlieb said in an interview, testing costs are $10,000 a patient for a four-month to six-month study, he added. Imreg-1 is being tested on patients with AIDS and a pre-AIDS condition known as AIDS-related complex. AIDS is a collapse of the immune system spread by sexual and blood contact. In both AIDS and the AIDS-related complex, immune system cells malfunction, leaving the body susceptible to infections and a cancer called Kaposi's Sarcoma. Dr. Gottlieb said he expects to make an announcement soon on a capital infusion from another company for more research, development and testing, and a licensing agreement for marketing. Dr. Gottlieb said Imreg-1 could have commercial licensing in a year and a half from the Food and Drug Administration. There are an estimated 300,000 people in the U. S. with AIDS-related complex and one million people infected by the virus that causes AIDS. AIDS-related complex patients are becoming a "very sizable potential market," Dr. Gottlieb said. The commercial cost of Imreg-1 would be "dollars per dose rather than hundreds of dollars per dose," he said. Thus far, Imreg-1 has shown no "overt toxicity" in patients. But, he said, "I don't want to make any broad claims." Imreg hopes to test the drug on patients with other diseases that have impaired immune systems, such as other cancers, juvenile diabetes and rheumatoid arthritis. (This article is made available here by Dow Jones Co. for the personal and non-commercial use of callers to this bbs, in the hope that it will be of some help to those who are suffering from the disease and others who are seeking to help them.)