Subject: Nature's way of telling you Date: Mon, 18 Sep 1995 03:31:59 -0700 (74 lines of text) From: todd33 at ix.netcom.com (Todd Miller ) The editorial in the September 7, 1995 issue of _Nature_, which accompanied the hemophilia study that the press is touting as "definitive" proof that HIV causes AIDS, contains some strong admonitions to those doubting the role of HIV. A few selected quotes that I will try to keep in context. Opening line: "Not much has recently been heard from those who hold that HIV has nothing or little to do with the causation of AIDS." Later: "It is well known that no amount of statistical argument can by itself prove that a disease is actually caused by the agent with which it is statistically associated. That is why some people still believe that cigarette smoking is not a cause of lung cancer and cardiovascular disease, for example. Even now, there will be ingenious people constructing hypotheses by which the association described can be explained by mechanisms other than those that appear to stare one in the face." "The view that AIDS is caused not by HIV as such but by the injection of drugs of various kinds, "recreational drugs" particularly, and also drugs used as medicines, will nevertheless be more difficult to sustain in the light of the evidence from Darby et al." "Yet is is safe to predict that there will be complaints from the obstinate community of the unconvinced that Darby et al. have failed to provide full details of the drug regimen followed by the 6,000 people on the register, and that until they do, their conclusion has no force." "The mistake in that opinion, if voiced, would be twofold. First, the data now published are of interest and importance in their own right, as further evidence (if such were needed) that HIV is almost invariably linked with AIDS. As such, they are addressed to the research and medical community at large, not to the company of the unconvinced. Second, the sad truth about debates on controversial issues in science is that there may come a point at which dissenters forfeit the right to make claims on other people's time and trouble by the poverty of their arguments and the exasperation they have caused. The world (to judge from Nature's postbag) is full of people who believe that Einstein's relativity is a pack of lies, but who cannot make the claim on other people's attention they would wish." "The tragedy, in the case of HIV and AIDS, is that disbelief in the role of HIV in AIDS has spread from beyond a small company in the research community to large part of the AIDS community itself. The reasons are unremarkable and pathetic in the strict sense of that word: it is at least uncomfortable for an infected person to know that HIV infection will lead eventually to AIDS. Not for nothing is the knowledge often called a "death sentence". The remedy is not, of course, to pander to wish-fufilment, but to redouble the effort in the laboratory and the clinic. Those who have made the running in the long controversy over HIV in AIDS, Dr Peter Duesberg of Berkeley, California, in particular, have a heavy responsibility that can only be discharged by a public acknowledgement or [sic?] error, honest or otherwise. And the sooner the better." Seems like an awful lot of rhetoric directed at those who are being painted as way out in left field. If the dissidents are that far removed, why bother even addressing the issue at all? This editorial suggests to me that there are some who are very concerned about the growing challenges to the HIV->AIDS theory. Todd Miller